A Virtual Biopsy

Magnetic Resonance Spectroscopy (MRS) provides a ‘virtual biopsy’ by measuring the concentrations of chemicals in the brain.

What we Do

Our Technology

BrainSpec is a comprehensive web-based software platform designed to make Magnetic Resonance Spectroscopy (MRS) technology accessible to both clinicians and researchers. The platform combines a highly accurate post-processing backend based on a linear combinations model with a user-friendly web-based interface. This combination ensures precise analysis while maintaining ease of use, resulting in more efficient case processing.

We are pioneering the development of the first-ever database for reference brain chemistry for use in clinical applications, as well as an extended database of diseased brain chemistry for use in a research context, streamlining MRS interpretation to be as straightforward as analyzing routine blood test results. 

Precision Metabolite Measurement

Cross Vendor Support

Automatic Reporting

Safe and Non-Invasive

Like an MRI, there is no harmful ionizing radiation with MRS

Cutting Edge Processing

Because we process all your data in the cloud, you always get the most up-to-date results

Standard Equipment

Standard MRI machines can acquire  MRS for analysis

Proven Clinical Utility

Over 28,000 publications describe the clinical use of MRS


The Essentials

Going beyond traditional imaging techniques, MR spectroscopy is used to analyze tissue metabolism, measuring metabolites at concentrations 10,000 times lower than conventional MRI. 

With proper analysis, this data can be used to form a ‘virtual biopsy’ of the brain, providing critical information about tissue composition without requiring a traditional surgical biopsy. 

This powerful technology has applications in patient populations with brain tumors, Alzheimer’s disease, Multiple Sclerosis and many other conditions.

Safe & Non-Invasive


Proven Clinical Utility

The Science

Nuts & Bolts

The nuclei of many elemental isotopes (1H, 13C, 19F and 31P, among others) have a characteristic spin, either ‘up’ or ‘down’, with one spin state higher in energy than the other. A spinning charge creates a magnetic field, and thus each elemental isotope has a unique magnetic moment. Within a given sample, the orientations of nuclear spin states are random. When placed in a large magnetic field, such as an MRI machine, however, the spin states all align with the field. With the application of energy—typically in the form of radio waves—a nucleus will flip from one spin state to the other. The frequency of energy that this flip requires is characteristic of the nucleus, but varies with the strength of the magnetic field and the electron shielding of other electrons in a molecule.

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Browse Literature

This powerful technology has applications in patient populations with brain tumors, Alzheimer’s disease, Multiple Sclerosis and many other conditions.

Contact Us

BrainSpec Core™ is currently pending FDA clearance. We are currently accepting a limited number of pilot sites for research use. Please contact us if you are interested.

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